Year: 2025
Type: article
Abstract: This paper presents a low-cost wireless prototype designed for point-of-care DNA sensing based on square wave voltammetry (SWV) measurements. Unlike other designs found in the literature, this prototype employs dedicated ADC and DAC components to reduce noise and allows for lower voltage steps in SWV scans. On-board signal processing makes the device suitable for use by inexperienced end-users. The prototype transmits data via Bluetooth Low-Energy (BLE) to a mobile app, which records the measurements on a cloud platform. The prototype was employed to detect a 23-base single-stranded DNA (ssDNA) sequence, within the range of 1 nM to 10 nM. The results obtained with the prototype showed good agreement when compared to a commercial electrochemical analyzer. This study demonstrates the feasibility of using such a device for DNA sensing, highlighting its potential for broader biosensing applications.
Source: Chemosensors
Language: English
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,413
OpenAlex ID: W4409061412