Primary cerebral lymphoma and autoimmune hepatitis: An unusual case associated with prolonged treatment with mycophenolate mofetil.
Year: 2025
Type: article
Study design: Case Report
Abstract: The initial approach to autoimmune hepatitis is based on the use of immunosuppressants and corticosteroids. The first-line immunosuppression options include azathioprine or mycophenolate mofetil. Long-term immunosuppression predisposes patients to the development of neoplastic diseases. In this case, chronic AIH treatment with mycophenolate mofetil was associated with the onset of primary cerebral lymphoma, which was treated with methotrexate and rituximab. Rituximab is an interesting therapy for AIH, and in this case, it was able to treat both conditions.
Authors: María Aragüés Floristán, Marta Obra Pinacho, Adolfo Jesús Sáez Marín, Ana Jiménez Ubieto, Ana Martín Algíbez, Inmaculada Fernández Vázquez, Elena Gómez Domínguez
Institution: Hospital Universitario 12 De Octubre
Language: English
Topic: Liver Diseases and Immunity
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4409068529