Work

The tell-tale hearts: Donor-derived invasive fungal infections among orthotopic heart transplant recipients

Year: 2025

Type: article

Abstract: Donor-derived invasive fungal infections among solid organ transplant recipients are rare but sometimes devastating events associated with notable morbidity and mortality. Here we describe two donor-derived fungal infections – one Candida parapsilosis complex infection and one Aspergillus fumigatus infection – that occurred among heart transplant recipients at a quaternary care center. Both recipients survived their infections, though with substantial morbidity despite aggressive surgical intervention and antifungal therapy.

Source: Medical Mycology Case Reports

DOI: 10.1016/j.mmcr.2025.100702

Authors: Jay Krishnan, Manuela Carugati, Rachel A. Miller, Cameron R. Wolfe, John R. Perfect, Julia A. Messina

Institutions: Duke University, Duke Medical Center

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $650