Supplementary Table 5 from Preclinical Development of SGN-CD47M: Protease-Activated Antibody Technology Enables Selective Tumor Targeting of the Innate Immune Checkpoint Receptor CD47
Year: 2025
Type: supplementary-materials
Abstract: Supplementary Table 5. Pharmacokinetic parameters of gTAb in monkey plasma following a single IV dose of hB6H12.3 (1 mg/kg) or SGN-CD47M (10 or 20 mg/kg) as determined by non-compartmental analysis.
Authors: Matthew R. Levengood, Christopher M. Carosino, Xinqun Zhang, Sasha Lucas, David J. Ortiz, Lori Westendorf, Alice P. Chin, Arlan D. Martin, Abbie Wong, Shawna M. Hengel, Hao Sun, Weiping Zeng, Roma Yumul, Melissa M.C. Dominguez, Yufei Chen, Janet H. Zheng, Courtney A.B. Karlsson, Vivian H. Trang, Peter D. Senter, Shyra J. Gardai
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4409079284