Supplemental Figure S19 from VAX014 Activates Tumor-Intrinsic STING and RIG-I to Promote the Development of Antitumor Immunity
Year: 2025
Type: supplementary-materials
Abstract: Supplemental Figure S19. Growth of MB49 STING KO and RIG-I KO i.d. tumors. 9-week-old female C57BL/6 mice were implanted with a single i.d. tumor on Day 0 and growth monitored until termination criteria were reached. A) Mean tumor growth rates and B) Kaplan-Meier survival curves for MB49WT (WT) and MB49STING KO (STING KO) tumors. C) Mean tumor growth rates and D) Kaplan-Meier survival curves for MB49 WT and MB49RIG-I KO (RIG-I KO) tumors. Mean tumor growth rates (mean ± SEM) were plotted until the median survival of the WT control. Student’s t test was used to analyze the significance of growth rates on Day 32. (n= 5-8/group). ns = not significant.
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4409079323