Work

The neurons that mediate a psychedelic’s long-term antidepressive effects

Year: 2025

Type: article

Abstract: Psilocybin, a classic psychedelic, has therapeutic potential for psychiatric disorders. A specific brain circuit and receptor have now been found to be required for psilocybin’s long-term effects on neural plasticity and depression-related behaviour. The psychedelic psilocybin’s beneficial behavioural action depends on the activation of pyramidal-tract neurons in the frontal cortex.

Source: Nature

DOI: 10.1038/d41586-025-00979-3

Language: English

Topic: Psychedelics and Drug Studies

Subfield: Clinical Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $12,690

OpenAlex ID: W4409087880

FWCI:

Cites: 5

Cited by:

Related to: 10