Work

Cover Feature: Unlocking Lignin′s Potential: Engineered Bacterial Laccases to Produce Biologically Active Molecules (ChemSusChem 7/2025)

Year: 2025

Type: article

Abstract: The Cover Feature shows laccases as biocatalysts with high potential in lignocellulose biorefineries. Protein engineering has enhanced their efficiency for valorizing lignin monomers into value-added biologically active molecules. This biocatalytic process is solvent-free, achieves faster reaction times, uses lower amounts of enzyme, and delivers excellent yields (up to 100 %). The work advances lignin combinatory chemistry knowledge and marks a step forward in producing sustainable and eco-friendly natural dimeric compounds for medicinal chemistry and polymer synthesis. More information can be found in the Research Article by M. P. Robalo, M. R. Ventura, L. O. Martins and co-workers (DOI: 10.1002/cssc.202401386). Cover design: Joel Arruda (ITQB-NOVA Science Communication Office).

Source: ChemSusChem

DOI: 10.1002/cssc.202580702

Authors: Vânia Brissos, Márcia Rénio, Magdalena A. Lejmel, Ricardo Estevinho, M. Paula Robalo, M. Rita Ventura, Lígia O. Martins

Institutions: Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, University of Lisbon, Universidade Politécnica de Lisboa, Instituto Superior Técnico, Centro de Química Estrutural

Language: English

Topic: Lignin and Wood Chemistry

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Responsible consumption and production

Open Access status: bronze

OpenAlex ID: W4409088945

FWCI:

Cites:

Cited by:

Related to: 10