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3,5-Dihydroxybenzoic Acid as a Potent Inhibitor of Tyrosine Phenol-Lyase Decreases Fecal Phenol Levels in Mice

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Year: 2025
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c00418
Authors: Takuma Kobayashi, Shiori Oishi, Kodai Hara, Misaki Matsui, Pedro Mena, Hiroshi Hashimoto, Kenji Watanabe, Noriyuki Miyoshi
Institutions: Shizuoka University, University of Shizuoka, University of Parma, Unité de Nutrition Humaine
Language: English

Topic: Gut microbiota and health
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: Japan Society for the Promotion of Science
Awards: 腸内細菌代謝物であるフェノールが生体に与える影響の評価と産生量に関わる因子の解析, Understanding a mechanism of an onset of colorectal cancer by colibactin and finding compounds inhibiting colibactin biosynthetic enzymes, G547724079, Intestinal bacterial catabolic metabolism of dietary steroids produces steroid hormone-like molecules
OpenAlex ID: W4409090625
FWCI: 1.567
Cites: 52
Cited by: 6
Related to: 10
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