Year: 2025
Type: article
Study design: Observational Study
Abstract: BACKGROUND:In recent years, with the ban on paraquat, the use of diquat (DQ) as a substitute has significantly increased, leading to a corresponding increase in DQ poisoning cases.This study aimed to identify relevant risk factors aff ecting patient prognosis and provide a basis for the assessment of patient prognosis. METHODS:Patients with DQ poisoning were included from September 2020 to December 2023, and data were extracted from their electronic medical records on the fi rst day of hospitalization.LASSO regression and binary multivariate logistic regression analyses were performed on the collected clinical data to identify risk factors. RESULTS:A total of 117 patients with acute DQ poisoning were included, and were categorized into two groups based on their 28-day outcomes: survival group (n=67) and non-survival group (n=50).There were no statistically significant differences between the two groups in terms of sex, lymphocyte count, platelet-to-lymphocyte ratio, or blood purifi cation rate (P>0.05).The analysis revealed that age (odds ratio [OR] 1.094, 95% confi dence interval [95% CI] 1.022-1.171),blood drug concentration (OR 3.659, 95% CI 1.846-7.252),lactate (OR 1.686, 95% CI 1.062-2.678),NLR (OR 1.101, 95% CI 1.017-1.192),albumin (OR 1.275, 95% CI 1.107-1.468),and AST (OR 1.027, 95% CI 1.005-1.051)were the optimal risk factors for mortality. CONCLUSION:This study identified key risk factors for 28-day mortality in patients with acute DQ poisoning, which may provide valuable guidance for clinical treatment, particularly for emergency physicians.
Authors: Qing Tang, Hongxin Wang, Hao Wang, Jiaqi Xu, Xin Luo, Shuxin Hua, Lijun Wang, Yanfen Chai
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4409100597