Work

Rare case report: primary small-cell neuroendocrine carcinoma of the gallbladder

Year: 2025

Type: article

Abstract: Gallbladder cancer (GBC) accounts for 1.7% of all cancer-related deaths. Neuroendocrine carcinoma of the gallbladder (GB-NEC) is a rare subtype of GBC that is more malignant than GBC. Small-cell neuroendocrine carcinoma of the gallbladder (GB-SCNEC) is a rare malignant tumor with a low incidence. To date, no universally accepted or satisfactory treatment exists. This case report details the clinical presentation, diagnostic process, and treatment strategy of a patient with GB-SCNEC. The analysis of this rare case is intended to provide clinicians with diagnostic and therapeutic insights for future research.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2025.1524974

Authors: Haichen Wang, Qinglin Li, Shaoqi Han, Hu Tian

Institutions: Shandong Provincial QianFoShan Hospital, Shandong First Medical University

Language: English

Topic: Cholangiocarcinoma and Gallbladder Cancer Studies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801