Selenium modulates perinatal pulmonary vascular responses to hyperoxia
Year: 2025
Type: article
Abstract: The data demonstrate a reduction in the number of pulmonary blood vessels in the setting of perinatal selenium deficiency that is exacerbated by postnatal O 2 exposure. RNA analysis of peripheral lung tissue indicated that changes in vessel density were associated with alterations in the transcription of genes responsible for maintenance of endothelial phenotype and homeostasis in our experimental bronchopulmonary dysplasia model.
Institution: University of Oklahoma Health Sciences Center
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funder: American Lung Association
Award: G4146223240
OpenAlex ID: W4409106751