Work

Untangling Mechanical Complications of Acute Myocardial Infarction

Year: 2025

Type: article

Abstract: Mechanical complications after acute myocardial infarction, including left ventricular free wall rupture, ventricular septal rupture, papillary muscle rupture, and pseudoaneurysm, although infrequent, are associated with significant morbidity and mortality. Despite the reduction in incidence because of early reperfusion therapies, their associated mortality rates remain disproportionately high. This disparity highlights the critical need for early detection and prompt intervention, which are key to improving patient outcomes in the postinfarction period. Timely restoration of coronary blood flow is essential for preventing complications, with reperfusion strategies, particularly percutaneous coronary intervention, serving as a cornerstone in minimizing ischemic injury. This review aims to provide an in-depth evaluation of the clinical, diagnostic, and therapeutic approaches to these mechanical complications with illustrative case studies to facilitate practical understanding of these conditions.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2025.103400

Authors: Yilmar Alexander Meza-González, María Carolina Manzur-Barbur, Andrés Felipe Ochoa-Díaz, Nicolas Ariza-Ordoñez, Juan Felipe Vásquez-Rodríguez, María Juliana Rodríguez- González

Institution: Universidad del Rosario

Language: English

Topic: Cardiac Structural Anomalies and Repair

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $850