Anti-Ulcer Activity of Ficus Glomerata Extract on Pylorus Ligation-Induced Gastric Ulcer In Experimental Animals
Year: 2025
Type: article
Abstract: The phytochemical investigation and assessment of the anti-ulcer properties of a hydroalcoholic extract of Ficus glomerata leaves are the focus of this work. The hydroalcoholic extract of Ficus glomerata on gastric ulcer pyloric ligation in rats was also used to test the ulcerative index, stomach volume, pH, and total and free acidity. A one-way ANOVA and Tukey's multiple comparison tests were used for statistical evaluation, and the findings were presented as Mean ± S.E.M. Only the hydro alcohol extract contains glycosides, alkaloids, carbohydrates, terpenoids, and flavonoids. Thus, for its anti-ulcer properties, the hydroalcoholic extraction was employed. The current investigation was conducted in albino rats using a pylorus ligation-induced gastric ulcer model. The hydroalcoholic extracts of Ficus glomerata were tested orally at a dose level of 200 mg/kg body weight and compared to the standard of ranitidine (10 mg/kg). According to the findings, hydro alcohol leaf extracts of Ficus glomerata at a dose level of 200 mg/kg shown a noteworthy anti-ulcer effect in comparison to the usual medication.
Source: Journal of Neonatal Surgery
Authors: Vaibhav P. Uplanchiwar, Mudita Mishra, Shalini Singh Negi, Mohammed Rageeb Mohammed Usman, Alka Mishra, Srishti Goyal, Preety Choudhary, Sivasubramanian P
Language: English
Subfield: Plant Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4409113841