Work

Functionalization of a Ru( ii ) polypyridine complex with an aldehyde group as a synthetic precursor for photodynamic therapy

Year: 2025

Type: article

Abstract: orbital is transferred to the π* ligand orbital in a metal-to-ligand charge transfer transition. The compound was found to be highly stable under physiological conditions as well as upon irradiation. Upon light exposure, the metal complex was found to efficiently convert molecular oxygen to singlet oxygen. These findings highlight the potential of the aldehyde functionalized Ru(II) polypyridyl complex as a versatile precursor for photodynamic therapy.

Source: Dalton Transactions

DOI: 10.1039/d5dt00256g

Authors: Lisa-Marie Servos, Hung Manh Tran, Nicolás Montesdeoca, Zisis Papadopoulos, Eun Sakong, Johannes Karges

Institution: Ruhr University Bochum

Language: English

Topic: Photodynamic Therapy Research Studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

Open Access status: hybrid

Funders: Verband der Chemischen Industrie, Fonds der Chemischen Industrie, Paul-Ehrlich-Gesellschaft Stiftung, Aventis Foundation

OpenAlex ID: W4409114722

FWCI: 3.038

Cites: 39

Cited by: 5

Related to: 10