Work

A Case of Rhabdomyosarcoma Arising in a Giant Congenital Melanocytic Nevus: Focus on Differential Diagnosis

Year: 2025

Type: article

Abstract: Background: Giant congenital melanocytic nevi (CMNs) are rare, disfiguring lesions with a significant potential for malignant transformation. Melanoma is the most common malignancy associated with giant CMNs. While exceedingly rare, other malignant tumors, such as mesenchymal neoplasms like rhabdomyosarcoma (RMS), may also develop in conjunction with giant CMNs. This report presents a case of progressive metastatic RMS originating from a giant CMN in a 19-year-old female, who presented with ipsilateral inguinal lymph node metastases.

Source: EJC Skin Cancer

DOI: 10.1016/j.ejcskn.2025.100443

Authors: N. Duman, B. Yaman, İ. Akçay, I. Karaarslan, B. Karaca Yayla

Institution: Ege University

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,340