Work

Diagnostic challenges and the critical role of early multidisciplinary management of acral melanoma

Year: 2025

Type: article

Abstract: Background: Acral melanoma (AM) and its amelanotic variant (AAM) are rare, aggressive melanomas that predominantly affect acral sites, including the palms, soles and subungual regions. These malignancies often mimic benign conditions such as warts, calluses or infections, leading to delayed diagnosis. The importance of timely diagnosis and early multidisciplinary intervention in AM is underlined by both individual case analyses and broader systematic reviews, which highlight significant gaps in diagnostic approaches, particularly the underutilisation of biopsies for lesions on the lower extremities.

Source: EJC Skin Cancer

DOI: 10.1016/j.ejcskn.2025.100421

Authors: F. Cassalia, P. Del Fiore, A. Danese, M. Soldà, V. Furfaro, S. Mocellin

Institutions: University of Padua, Istituto Oncologico Veneto, University of Verona

Language: English

Topic: Cutaneous Melanoma Detection and Management

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,340