Work

Development of a molecular assay for multiomic detection of cfDNA signals in blood samples from skin cancer patients

Year: 2025

Type: article

Abstract: Background: Skin cancer is one of the most common forms of cancer, and it is projected to become a significant public health problem in Europe.Basal-cell skin cancer (BCC) and squamous-cell skin cance (SCC) rarely result in death, whilst the survival rate of melanoma is highly dependent on the stage.This means that the early detection of skin cancer, especially melanoma is of paramount importance.The objective of this study is to develop a comprehensive multi-omic blood-based test for early detection of skin cancer based on the Oxford Nanopore Technology.

Source: EJC Skin Cancer

DOI: 10.1016/j.ejcskn.2025.100405

Authors: A. Ilieva, S. Mehandziska, M. Gjorgjievska, G. Kungulovski, A. Lallas

Institutions: Goce Delcev University, Aristotle University of Thessaloniki

Language: English

Topic: Cancer Genomics and Diagnostics

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,340