Year: 2025
Type: article
Abstract: With an increasing awareness of health and the rapid development of biotechnology, semiconductor biochips, as an important tool at the intersection of integrated circuits and biomedical fields, have shown great potential in disease monitoring and other areas. This paper analyzes the working principles of semiconductor biochips and their specific applications in disease detection, exploring how they achieve early disease diagnosis by monitoring changes in biomarkers such as ion concentration and metabolic products. Through literature review and case analysis, this study summarizes the current mainstream types of biochips (such as microfluidic chips and electrochemical sensor chips) and their effectiveness in monitoring diseases like cancer and diabetes. The results indicate that semiconductor biochips offer advantages such as high sensitivity, rapid response, and low cost, but they still face challenges in biocompatibility and large-scale production. In the future, with advancements in materials science and nanotechnology, biochips are expected to play a more significant role in personalized medicine and point-of-care testing (POCT).
Author: Zetian Fu
Institution: UNSW Sydney
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: hybrid
OpenAlex ID: W4409118596