Work

Outcome measures reported by cancer patients treated with tyrosine kinase inhibitors: a methodological study.

Year: 2025

Type: article

Abstract: OBJECTIVES: to validate the content of an outcome measurement instrument with expert judges and to assess the understandability and suitability of this validated instrument with cancer patients undergoing tyrosine kinase inhibitor (TKI) therapy. METHODS: a methodological study, which included the development of an instrument through integrative review, content validity, using the Delphi technique with expert judges, and pilot testing, to verify users' understandability and suitability to the instrument. RESULTS: literature review allowed constructing PRO-CTCAE® Estudo PROM-TKI Brasil, with 16 items, which was later submitted to validity using the Delphi technique. After the second round, the final instrument consisted of 20 items, with a Content Validity Index (CVI) of 0.878. The pilot test showed that the instrument is understandable and suitable for the target population (CVI of 1.0). CONCLUSIONS: PRO-CTCAE® Estudo PROM-TKI Brasil obtained evidence of validity for use during TKI therapy.

Source: PubMed

DOI: 10.1590/0034-7167-2024-0018

Authors: Ana Maria Teixeira Pires, Julie Ann Ponto, Eliana Cavalari Teraoka, Fabio Rodrigues Kerbauy, Edvane Birelo Lopes De Domenico

Institutions: Universidade Federal de São Paulo, Winona State University

Language: English

Topic: Health Education and Validation

Subfield: Education

Field: Social Sciences

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4409118806

FWCI:

Cites: 1

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Related to: 10