Work

SR Protein Kinase is expressed in Drosophila ovarian germline stem cells but is not essential for their self-renewal

Year: 2025

Type: article

Abstract: ) is essential for GSC self-renewal. We find that SRPK is expressed in GSCs and their mitotically-dividing daughters, but is not necessary for GSC establishment or maintenance. We conclude that SRPK is dispensable for GSC self-renewal, and postulate that other protein kinases can compensate for its absence.

Source: PubMed

DOI: 10.17912/micropub.biology.001550

Authors: Victoria E. Garrido, William G. Outlaw, Amanda M. Powell, Elizabeth T. Ables

Institution: East Carolina University

Language: English

Topic: Developmental Biology and Gene Regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences

Awards: G3403299208, Molecular mechanisms of oocyte development in Drosophila