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Quantitative Systems Pharmacology (QSP) Analysis of Medicinal Mechanisms for Heart and Kidney Function Enhancement, and Optimal Dosage Strategies for Odronextamab in B-NHL Patients

Year: 2025

Type: article

Abstract: This study investigates the mechanisms of medications impacting heart and kidney function and optimizes dosing strategies for Odronextamab. Utilizing secondary source data and a comprehensive Quantitative systems pharmacology (QSP), the research unveils hidden salt loss mechanisms, explores medication impacts on cardiovascular health, and recommends a personalized dosing regimen for Odronextamab. Validation against real-world data ensures the model's accuracy. Clinical implications emphasize the model's role in understanding drug safety and efficacy, providing guidance for B-NHL patients.

Source: Journal of Neonatal Surgery

DOI: 10.52783/jns.v14.2251

Authors: Mohd Tabish, Kamran Javed Naquvi

Institution: Mangalayatan University

Language: English

Topic: Pharmaceutical studies and practices

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4409144759

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