Work

Emerging mechanobiology techniques to probe intracellular mechanics

Year: 2025

Type: article

Abstract: Studying the physical properties of sub-cellular components is increasingly important in understanding cell mechanics. This review focuses on the most advanced techniques available for investigating intracellular mechanics. We distinguish methods that act as force generators and those that act as force sensors. We highlight six state-of-the-art techniques, with increased spatial and temporal resolutions: optogenetics, Brillouin microscopy, bacterial cells and nanorobots, optical tweezers, membrane tension probes, and magnetic particles.

Source: npj Biological Physics and Mechanics.

DOI: 10.1038/s44341-025-00016-4

Authors: Kelly Molnar, Jean-Baptiste Manneville

Institutions: Centre National de la Recherche Scientifique, Université Paris Cité, Laboratoire Matière et Systèmes Complexes

Language: English

Topic: Cellular Mechanics and Interactions

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $2,490

Funder: Agence Nationale de la Recherche