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Interesting cases of microangiopathic hemolytic anemia

Year: 2024
Type: article
Abstract: Microangiopathic hemolytic anemia (MAHA) is a type of hemolytic anemia where there is fragmentation and hemolysis due to damage of erythrocytes in the small blood vessels. The initial evaluation is focused on confirming MAHA and thrombocytopenia and excluding systemic disorders that manifest these findings/mimic thrombotic thrombocytopenic purpura. All patients with a suspected primary thrombotic microangiopathy should have a thorough laboratory workup. ADAMTS13 activity is measured before starting therapeutic plasma exchange (TPE). The immediate management decision is whether to perform TPE or to start anti-complement therapy. Management depends on the specific syndrome.
Authors: Nilesh Wasekar, Shivani Joshi
Institution: Medicover Hospitals
Language: English
Subfield: Immunology
Open Access status: hybrid
OpenAlex ID: W4409168158
FWCI:
Cites: 6
Cited by:
Related to: 10