Work

The association between magnesium depletion score (MDS) and overactive bladder (OAB) among the U.S. population

Year: 2025

Type: article

Abstract: OBJECTIVE: This study aimed to assess the relationship between magnesium depletion score (MDS) and overactive bladder (OAB) prevalence. METHODS: This study utilized data from the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2018. Multivariate logistic regression was employed to investigate the association between MDS and OAB. Restricted cubic spline (RCS) analysis explored the linear or non-linear relationship between MDS and OAB. Interaction analyses were conducted on subgroups to validate the findings. RESULTS: There was a significant positive association between MDS and OAB. After adjusting for covariates, with each unit increase in MDS, there was an 11% increase in the prevalence of infertility (P < 0.001). In addition, the incidence of OAB was significantly increased in the higher MDS group compared to the low MDS group (MDS = 0) (P for trend < 0.001). The dose-response curve indicated a linear association between MDS and OAB, with higher MDS associated with higher OAB. CONCLUSION: The results of this study show a strong positive correlation between MDS and the prevalence of OAB. These findings suggest that monitoring and managing magnesium status may be a potential strategy for reducing the risk of OAB.

Source: Journal of Health Population and Nutrition

DOI: 10.1186/s41043-025-00846-x

Authors: Hongyang Gong, Weimin Zhao, Seok Choi, Shaoqun Huang

Institutions: Fujian University of Traditional Chinese Medicine, Chosun University, Shihezi University

Language: English

Topic: Urinary Bladder and Prostate Research

Subfield: Urology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,790