Clonidine Induced Acute Colonic Pseudo-obstruction: A Rare Adverse Effect
Year: 2025
Type: article
Study design: Case Report
Abstract: Objectives: Acute colonic pseudo-obstruction is a massive colonic dilation with signs and symptoms of colonic obstruction, but without a mechanical cause. Methodology: A 73-year-old hypertensive male on clonidine therapy developed spontaneous left basal ganglia haemorrhage with interventricular haemorrhage. While undergoing neurological treatment patient developed abdominal distension and constipation during hospital stay. All investigations done lead to the diagnosis of Acute colonic pseudo-obstruction (ACPO) (Ogilvie Syndrome). Results: Clonidine was suspected cause of Acute colonic pseudo-obstruction (ACPO). Hence clonidine was stopped and patient gradually improved.
Source: Apollo Medicine
Authors: Richa Bachani, Prayas Bachani, Deepak Malhotra
Institution: Apollo Hospitals
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409172683