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Na-Ag Ion-Exchanged Glass Substrates for Plasmon-Enhanced Fluorescence Imaging of Neutrophils

Year: 2025
Type: article
Abstract: Here, we study the fluorescence response of neutrophils stained with the wheat germ agglutinin Alexa Fluor 594 dye when the cells are placed on plasmonic nanoparticle substrates. Specifically, we focused on gold and silver nanoparticles with particle sizes ranging from 12 to 250 nm. It was demonstrated that the intensity of fluorescence can be increased by more than 10 times when using substrates with silver nanoparticles formed by Na+-Ag+ ion exchange in glass. The fluorescence enhancement depends significantly on both the size and surface density of the silver nanoparticles and the membrane staining procedure.
Source: Sensors
DOI: 10.3390/s25072278
Authors: Vladimir A. Inozemtsev, Maxim E. Dokukin, Yevgeniy M. Sgibnev, Ekaterina A. Sherstyukova, Snezhanna S. Kandrashina, Mikhail A. Shvedov, Artem V. Shelaev, Nikolay V. Nikonorov, Viktoria A. Sergunova, Alexander V. Baryshev
Language: English
Open Access status: gold
Estimated APC paid: $3,137
OpenAlex ID: W4409173059
FWCI:
Cites: 60
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Related to: 10