Work

Stereochemical matching determines both helix type and handedness in α/γ-peptides with a cyclic-constrained γ-amino acid

Year: 2025

Type: article

Abstract: )-alanine a left-handed 12 helical architecture is promoted. Experimental evidence for this dichotomy was obtained by detailed analysis of the IR amide I and II absorption bands and their assignments with assistance from theoretical simulations.

Source: Chemical Communications

DOI: 10.1039/d5cc00746a

Authors: Dayi Liu, Ali T. Mansour, Ogaritte Yazbeck, Daoud Naoufal, Sylvie Robin, Eric Gloaguen, Valérie Brenner, Michel Mons, David J. Aitken

Institutions: Centre National de la Recherche Scientifique, Université Paris-Saclay, Institut de Chimie Moléculaire et des Matériaux d'Orsay, Lebanese University, Université Paris Cité, Institut des Sciences Moléculaires d'Orsay, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Institut Rayonnement-Matière de Saclay, CEA Paris-Saclay - Etablissement de Saclay, Laboratoire Interactions, Dynamiques et Lasers

Language: English

Topic: Chemical Synthesis and Analysis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Funders: Agence Nationale de la Recherche, China Scholarship Council

Award: Tuning foldable building blocks using sulfur

OpenAlex ID: W4409175661

FWCI: 0.52

Cites: 41

Cited by: 2

Related to: 10