Work

Mechanochemical Synthesis of Pillar[5]arene‐based [c2]Daisy Chain Rotaxanes

Year: 2025

Type: article

Abstract: The solvent‐free mechanochemical acylation of pillar[5]arene‐based daisy chain monomers bearing either an alcohol or an amine function has been investigated in details. These chemical transformations have been also carried out in solution for comparison purposes. Whereas stoppered [c2]daisy chain derivatives have been obtained from the amine monomer whatever the conditions, stoppered [c2]daisy chain derivatives could be only obtained from the corresponding alcohol under mechanochemical conditions. In this particular case, concentration effects are clearly beneficial when the reactions are performed under solvent‐free conditions as daisy chain assemblies are effectively present in the solid state despite the very weak affinity of the 11‐hydroxy‐undecyl subunit for the pillar[5]arene moiety.

Source: ChemistryEurope

DOI: 10.1002/ceur.202500002

Authors: Boram Park, Iwona Nierengarten, Jean‐François Nierengarten

Institutions: Centre National de la Recherche Scientifique, Laboratoire de Chimie Moléculaire, Laboratoire d'innovation moléculaire et applications, Université de Strasbourg

Language: English

Topic: Supramolecular Chemistry and Complexes

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funder: Agence Nationale de la Recherche

Awards: Pillar[5]arene-based molecular machines, G3010527862, Mechanisms of ultraFast electron transfers in Giant polyrotaxanes, G6803667113