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The Impact of Channel Geometry and Flow Regime on Endothelial Orientation and Morphology in Vessel‐on‐Chip (Adv. Mater. Technol. 7/2025)

Year: 2025

Type: article

Abstract: Vessel-on-Chips In article number 2401994, Jaap M.J. den Toonder and co-workers explore how channel geometry and flow conditions affect blood and lymphatic endothelial cell orientation and morphology in vessel-on-chip models. Different flow conditions result in very different cell morphology in channels with circular and rectangular cross-section. Also, endothelial cell orientation induced by flow affects monocyte-endothelium interaction, crucial for understanding immune cell motility.

Source: Advanced Materials Technologies

DOI: 10.1002/admt.202570039

Authors: Mohammad Jouybar, Sophie van der Kallen, Sheen Sahebali, Carlijn Bouten, Jaap M.J. den Toonder

Institution: Eindhoven University of Technology

Language: English

Topic: 3D Printing in Biomedical Research

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W4409183677

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