Work

Hypoglycaemic Unawareness in a Glycogen Storage Disorder Patient: A Case Report and Review of the Literature

Year: 2025

Type: article

Abstract: The concept of hypoglycaemic unawareness is often discussed in the literature in relation to diabetics on insulin treatment. Hypoglycaemic unawareness is a state in which patients fail to recognize neuroglycopenic symptoms and signs that could prompt the need to seek measures to reverse or treat low blood sugar readings. This can lead to serious dangers, as immediate action is vital to avert potentially life-threatening consequences. We present a finding of hypoglycaemic unawareness in a 27-year-old female with a long-term diagnosis of Von Gierke disease (a glycogen storage disorder (GSD)) who went on to be fitted with a continuous glucose monitoring (CGM) device to prevent the harmful effects of unrecognised hypoglycaemia. We have reviewed the burden and probable mechanism for the development of hypoglycaemic unawareness in this disorder and in other infrequently reported disorders for the education of health professionals and patients.

Source: Cureus

DOI: 10.7759/cureus.81805

Authors: Alamin Alkundi, Rabiu Momoh

Institutions: East Kent Hospitals University NHS Foundation Trust, Medway Maritime Hospital

Language: English

Topic: Diabetes Management and Research

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4409201283