Work

Design, synthesis and bio-evaluation of 2,5-disubstituted thiazole derivatives for potential treatment of acute myeloid leukemia through targeting CDK9

Year: 2025

Type: article

Source: Bioorganic Chemistry

DOI: 10.1016/j.bioorg.2025.108436

Authors: Sumeng Chen, Jindi Huang, Shipeng Zhang, Xinni Zheng, Hongming Chen, Tie-Gen Chen, Ling Wang

Institutions: Guangdong Key Laboratory of Fermentation and Enzyme Engineering, South China University of Technology, Chinese Academy of Sciences, Shanghai Institute of Materia Medica, Guangzhou Laboratory

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Chinese Academy of Sciences, Natural Science Foundation of Guangdong Province, Zhongshan Science and Technology Bureau

Awards: G1164635587, G5877390273, G6719753581

OpenAlex ID: W4409208354

FWCI: 0.289

Cites: 38

Cited by: 1

Related to: 10