Work

PET/CT with 68Ga-FAPI and 18F-FDG in the Detection of Metastases in Regional Lymph Nodes in Gastric Cancer

Year: 2025

Type: article

Abstract: Purpose: To determine the diagnostic effectiveness of PET/CT with 68Ga-FAPI in gastric cancer. Matreial and Methods:The study included 42 patients with histologically confirmed gastric cancer. All patients underwent PET/CT with 68Ga-FAPI and PET/CT with 18F-FDG. The diagnostic accuracy of the methods was compared based on sensitivity and specificity parameters in detecting metastatic involvement of regional lymph nodes. Data assessment was conducted based on histologically verified disease and clinical follow-up data. Results: PET/CT with 68Ga-FAPI is a more effective diagnostic method for detecting metastases in regional lymph nodes compared to PET/CT with 18F-FDG. Our results support the clinical potential of PET/CT with 68Ga-FAPI for improved diagnosis and treatment planning in gastric cancer.

Source: Journal of oncology diagnostic radiology and radiotherapy

DOI: 10.37174/2587-7593-2025-8-1-29-35

Authors: E. V. Belkin, P. E. Tulin, O. B. Abu-Khaydar, I. A. Skripachev, A. V. Filimonov

Institution: Russian Cancer Research Center NN Blokhin

Language: English

Topic: Peptidase Inhibition and Analysis

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4409208638

FWCI: 1.117

Cites: 17

Cited by: 3

Related to: 10