Work

IL1A: a novel prognostic biomarker and potential therapeutic target for renal clear cell carcinoma

Year: 2025

Type: article

Abstract: Background: Renal cell carcinoma (RCC) is a prevalent malignancy characterized by a rising incidence and significant mortality. Interleukins (ILs) are crucial in regulating immune cell trafficking and exhibit anti-tumor properties. However, limited research has explored the expression levels and prognostic significance of interleukins in RCC. Methods: In this comprehensive study, we performed a detailed analysis of interleukins in RCC patients using multiple bioinformatics tools, including Oncomine, UALCAN, GEPIA, Kaplan-Meier plotter, cBioPortal, GeneMANIA, TRRUST, STRING, and Linked Omics. Results: and clinical studies. Conclusion: and clinical investigations.

Source: Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics

DOI: 10.32604/or.2025.061978

Authors: JI ZENG, XUETENG MENG, YUAN ZHANG, JUN LI, TAOTAO MA, CHENG HUANG

Institutions: Anhui Medical University, Hefei First People's Hospital

Language: English

Topic: Renal cell carcinoma treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4409209871

FWCI: 1.181

Cites:

Cited by: 2

Related to: 10