Work

Investigating the effects of silk fibroin on ultrasound-mediated ultrafine bubble drug transport and delivery systems

Year: 2025

Type: article

Abstract: silkworm) in conjugation with polyethylene glycol 400 to stabilize the ultrafine bubble drug loading and releasing system. Light scattering laser imaging was used to examine the effects of SF and PEG on system stability. In addition, fluorescence laser imaging and optical absorbance measurements were performed to assess the role of these additives in the drug encapsulation and release process. Results confirmed the bubble stability was enhanced by the introduction of SF and PEG into the drug-carrier system. This study demonstrated that the proposed drug-transportation system possessed an encapsulation capacity of more than 80% and a substantial released drug content of up to 50% after the application of ultrasonic radiation.

Source: RSC Advances

DOI: 10.1039/d5ra00334b

Authors: Nguyen Le Hanh Tran, Tam Vo Viet Tran, Khoi Le Minh Tran, Thu Phan Anh Le, Khoi Tan Nguyen

Institution: Vietnam National University Ho Chi Minh City

Language: English

Topic: Ultrasound and Hyperthermia Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042