Work

Author response: Ab initio prediction of specific phospholipid complexes and membrane association of HIV-1 MPER antibodies by multi-scale simulations

Year: 2025

Type: peer-review

Abstract: Molecular dynamics simulations reveal that lipid binding at antibody loops and framework regions stabilizes membrane interactions, providing molecular details for neutralization mechanisms and strategies for HIV-1 vaccine development.

DOI: 10.7554/elife.90139.3.sa3

Authors: Marco Mravic, Colleen A Maillie, Kiana Golden, Ian A Wilson, Andrew B Ward

Institution: Scripps Research Institute

Language: English

Topic: HIV Research and Treatment

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

Open Access status: gold

Funder: National Institute of Allergy and Infectious Diseases

Awards: G690068069, G8103778937

OpenAlex ID: W4409217052

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