Work

COVID‐19 Challenges in Autoimmune Hepatitis Management: A Successful Outcome With Intravenous Immune Globulin (IVIg)

Year: 2025

Type: article

Abstract: Background: Several autoimmune diseases, such as autoimmune hepatitis (AIH), can arise or become decompensated following COVID‐19 infection or vaccination; however, there is a lack of data regarding the management of concurrent COVID‐19 infection and autoimmune diseases. Case Summary: In this paper, we present a case of a 9‐year‐old boy with yellowish discoloration of the skin and sclera, abnormal liver function test, followed by positive qRT‐PCR for SARS‐CoV‐2 and progressive bicytopenia. After a lack of response to corticosteroids, intravenous immune globulin (IVIg) was administrated and a decline in liver enzymes, total bilirubin, and direct bilirubin was observed. Result and Discussion: This case illustrates how IVIg significantly improved the AIH symptoms in the patient with positive qRT‐PCR for the SARS‐CoV‐2 test. We hope our report encourages further research on therapeutic approaches for AIH concomitant with COVID‐19.

Source: Case Reports in Gastrointestinal Medicine

DOI: 10.1155/crgm/4446896

Authors: Amirali Mashhadiagha, Parnian Khalili, Maryam Ataollahi, Fereshteh Karbasian, Ali Arman, Bita Geramizadeh

Institutions: Shiraz University of Medical Sciences, Iran University of Medical Sciences

Language: English

Topic: Liver Diseases and Immunity

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $790