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Primary Small Cell Neuroendocrine Carcinoma of the Mediastinum: Case Report of a Rare Entity

Year: 2025

Type: article

Abstract: Small neuroendocrine carcinoma of the mediastinum (SCNCM) is a rare subtype of neuroendocrine malignancy characterized by its aggressive behavior and high rates of recurrence and metastasis. The diagnosis of this carcinoma is challenging, requiring confirmation through histopathological and immunohistochemical analysis, as well as specific imaging studies. This study reports a case of primary SCNCM that resulted in the death of a 59-year-old female patient treated at the Clinical Hospital, School of Medicine, Botucatu. The diagnostic proposal of primary small cell neuroendocrine carcinoma of the mediastinum was confirmed after a detailed analysis of the organs in an autopsy examination.

Source: Brazilian Journal of Case Reports

DOI: 10.52600/2763-583x.bjcr.2025.5.1.bjcr79

Authors: Magno Giovani Zanellato, Elida Paula Benquique Ojopi, Daniela Cristina dos Santos Souza

Institutions: Universidade Estadual Paulista (Unesp), Binzhou Medical College Hospital

Language: English

Topic: Neuroendocrine Tumor Research Advances

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4409224481

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