Work

Discovery of novel Ebola entry inhibitors with 1,2,3,4-tetrahydroisoquinoline-3-carboxamide based on (3S,4aS,8aS)-2-(3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold

Year: 2025

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2025.130230

Authors: Junzhen Lin, Fuling Xiao, Sheng Han, Youhong Hu, Jianping Zuo, Xiankun Tong, Wuhong Chen

Institutions: Chinese Academy of Sciences, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, State Key Laboratory of Drug Research, Nanjing University of Chinese Medicine

Language: English

Topic: Viral Infections and Outbreaks Research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Awards: G2342033366, G293496242, G8824936162

OpenAlex ID: W4409224916

FWCI: 0.732

Cites: 14

Cited by: 1

Related to: 10