Work

Enhancing ultrasound applications through shell-less nanobubbles: A study on acoustic and optical properties

Year: 2025

Type: article

Abstract: Shell-less nanobubbles, characterized by high internal pressure, high stability, negatively charged surfaces, and a unique lifetime ranging from several weeks to months, have recently been widely applied in agriculture and industry. However, there has been limited research exploring their interactions with ultrasound. To investigate these interactions, this study used a claw-type pump nanobubble generator to produce nanobubbles and employed acoustic and optical methods to observe the state of nanobubbles under high-intensity ultrasound exposure. The results showed that the device could generate nanobubble solutions with an average particle size of 107 nm, a concentration of 1.94×109 particles/mL, a lifetime exceeding 1 week, and a zeta potential of -43.7 mV. Acoustic and optical observations revealed that NB solutions reduced the inertial cavitation threshold of the liquid from 26.5 MPa to 10.3 MPa. These findings may provide a potential approach to enhance the treatment efficiency of ultrasound histotripsy.

Source: Ultrasonics Sonochemistry

DOI: 10.1016/j.ultsonch.2025.107336

Authors: Zong-Han Hsieh, Cheng-An J. Lin, Chih-Kuang Yeh

Institutions: National Tsing Hua University, Chung Yuan Christian University

Language: English

Topic: Ultrasound and Hyperthermia Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $3,710

Funders: National Science and Technology Council, National Science and Technology Council