Year: 2025
Type: article
Abstract: This study reviewed allergic transfusion reactions (ATRs) and the efficacy of pre-transfusion antihistamine (PreTAH) administration.Studies have shown that PreTAH does not prevent all ATRs and provides no significant benefit over non-administration groups.Instead, they may cause sedation, increase the burden on medical staff, and lack cost-effectiveness.Most transfused patients do not experience ATRs; except for anaphylaxis, they pose minimal risk.Thus, the decision to administer PreTAH should carefully weigh the benefits and risks.Routine PreTAH use in all transfusion patients is not recommended.Instead, PreTAH should be reserved for patients with a high risk of allergic reactions based on their medical history and risk factors.(Korean J Blood Transfus
Author: Young Ae Lim
Institution: Ajou University
Language: English
Subfield: Biochemistry
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4409239664