Work

Gastric metastasis from high-grade soft tissue sarcoma: a rare occurrence with literature review

Year: 2025

Type: article

Abstract: Metastasis of high-grade soft tissue sarcoma to the stomach is an extremely rare occurrence. While sarcomas can spread to distant organs, they most commonly metastasize to the lungs, liver, and bones. We report a unique case of gastric metastasis from a high-grade soft tissue sarcoma, occurring 4 years after the initial diagnosis of fibrosarcoma in the right femoral region. The patient did not undergo adjuvant chemotherapy and developed a large soft tissue metastasis in the left gluteal region 2 years later. After 4 years, he presented with a second soft tissue metastasis and suspected metastatic lung nodules. Symptoms of melena and severe anemia prompted a gastroscopic examination, which revealed gastric metastasis from a high-grade soft tissue sarcoma. Due to severe anemia, a palliative gastric resection was performed. A review of the literature indicates that metastatic leiomyosarcomas are the most frequently reported sarcoma subtype metastasizing to the stomach.

Source: Journal of Surgical Case Reports

DOI: 10.1093/jscr/rjaf192