Work

Electroorganocatalytic asymmetric Diels–Alder cycloaddition of hydroquinones with α,β-unsaturated aldehydes

Year: 2025

Type: article

Abstract: The concept of combining asymmetric aminocatalysis with electrochemistry remains underexplored. Herein, we report an electrochemically driven Diels-Alder cycloaddition reaction of substituted hydroquinones with a series of enals activated by a TMS-protected prolinol catalyst, leading to optically active products with high yields and perfect enantiomeric ratios up to 99 : 1 e.r.

Source: Chemical Communications

DOI: 10.1039/d5cc00505a

Authors: Dominika Pomikło, Krzysztof Romaniuk, Lesław Sieroń, Anna Albrecht

Institution: Lodz University of Technology

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Funder: Narodowym Centrum Nauki

Award: G3898365872