Work

NK/T-cell bone lymphoma-induced hemophagocytic lymphohistiocytosis: A clinical case report

Year: 2025

Type: article

Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a severe condition characterized by the secretion of large amounts of inflammatory cytokines. Lymphoma is a major cause of secondary HLH. This report describes the case of a child initially diagnosed with HLH who experienced recurrent episodes after treatment. Ten months after the initial diagnosis, a mass was discovered in the right upper limb, and pathology findings confirmed NK/T-cell lymphoma. Based on the patient's medical history, this lymphoma was considered the underlying cause of HLH. Patients diagnosed with lymphoma complicated by HLH have a worse prognosis and shorter survival compared with those without HLH. Early diagnosis and timely symptomatic treatment can significantly improve patient prognosis.

Source: Radiology Case Reports

DOI: 10.1016/j.radcr.2025.03.025

Authors: Zhanrong Zhang, Feng Chen

Institutions: Hainan General Hospital, Hainan Medical University

Language: English

Topic: Autoimmune and Inflammatory Disorders Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $600