The strong unstable manifold and periodic solutions in differential delay equations with cyclic monotone negative feedback
Year: 2025
Type: article
Abstract: For a class of $ (N+1) $-dimensional systems of differential delay equations with a cyclic and monotone negative feedback structure, we construct a two-dimensional invariant manifold, on which phase curves spiral outward towards a bounding periodic orbit. For this to happen, we assume essentially only instability of the zero equilibrium. Methods of the Poincaré-Bendixson theory due to Mallet-Paret and Sell are combined with techniques used by Walther for the scalar case $ (N = 0) $. Statements on the attractor location and on parameter borders concerning stability and oscillation are included. The results apply to models for gene regulatory systems, e.g. the 'repressilator' system.
DOI: 10.3934/cpaa.2025057
Authors: Anatoli F. Ivanov, Bernhard Lani-Wayda
Language: English
Subfield: Geometry and Topology
Field: Mathematics
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4409273995