Work

Ligand‐Enabled Photoinduced Ruthenium Catalysis for Ortho ‐C─O Bond Formation at Room Temperature

Year: 2025

Type: article

Abstract: Photoinduced ruthenium-catalyzed ortho-benzoxylation through organophosphine ligand is unveiled. The in situ generation of the organophosphine-ruthenium complex facilitates ligand-to-metal charge transfer (LMCT) under visible light, promoting the site-selective ortho-benzoxylation at room temperature. The broad scope of aryl, aliphatic, and heterocyclic carboxylic acids are key attractions of this methodology. EPR and UV-Vis analysis support a LMCT process between a photoexcited organophosphine and Ru-complex under blue-light irradiation. Comprehensive mechanistic investigation highlights the role of light, ligands, oxidants, the LMCT process, and the unique reactivity of the directing group.

Source: Chemistry - A European Journal

DOI: 10.1002/chem.202500711

Authors: Chandrasekaran Sivaraj, Ajay Thonipalliyalil Udayan, Karthick Muthuvel, Thirumanavelan Gandhi

Institution: Vellore Institute of Technology University

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funders: Council of Scientific and Industrial Research, India, VIT University, Science and Engineering Research Board, Science for Equity, Empowerment and Development Division

Awards: G5075413386, G8604090677, G935023231