Congenitally corrected transposition of the great arteries: one disease, diverse manifestations—a case series
Year: 2025
Type: article
Study design: Case Report
Abstract: Background: Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital heart defect with heterogenous clinical manifestations that can pose both diagnostic and management challenges throughout life. Case summary: We describe four patients with ccTGA and different presentations including sudden cardiac arrest, progressive heart failure, post-partum heart failure, and NSTEMI. Aims and Discussion: This case series aims to illustrate the importance of multimodality imaging to assist the diagnosis and support treatment strategies in patients with ccTGA. Direct long-term sequalae, such as arrythmias and heart failure, and the associated management challenges are highlighted. Additionally, the challenges of managing pregnancy with a sRV and the development of acquired heart disease demonstrate the clinical care challenges in caring for this population across the life span.
Institutions: Universität Hamburg, Yonsei University, Severance Hospital, Yonsei University Health System, Dokkyo Medical University Saitama Medical Center, Dokkyo Medical University, National Heart Institute, The Royal Melbourne Hospital, The University of Melbourne, Walter and Eliza Hall Institute of Medical Research, National Cerebral and Cardiovascular Center
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $815
OpenAlex ID: W4409275277