Year: 2025
Type: article
Study design: Case Report
Abstract: The relevance, pathogenesis, classification, and clinical characteristics of a rare disease-subacute cutaneous lupus erythematosus-are presented. A clinical case in a 60-year-old woman without signs of organ pathology is also described. A dermatoscopic examination was performed. In the affected areas on the facial skin, twisted, short linear, occasionally branching, unfocused vessels, predominantly bright red in color, forming incomplete polygonal structures, were identified. In the affected areas on the skin of the extremities, irregularly arranged dotted-granular and twisted short linear vessels of dull red color were visualized, along with structureless zones of varying degrees of discoloration, exhibiting whitish-orange shades. Pathomorphologically, the process is characterized by mild focal hyperkeratosis, vacuolar degeneration of the basal layer of the epidermis, a mildly expressed perivascular lymphohistiocytic inflammatory infiltrate, as well as a moderately expressed periadnexal (perieccrine) lymphohistiocytic inflammatory infiltrate.Based on the medical history, clinical presentation, and the results of dermoscopic and histological examinations, the diagnosis of psoriasiform subacute cutaneous lupus erythematosus was established.
Authors: Khachik Khachikyan, Hovhannes Hovhannisyan, Armine Hakobyan, Anj Giragos, Anahit T Topchyan
Institution: Yerevan State Medical University
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4409278006