Meet the author: Tychele N. Turner, PhD
Year: 2025
Type: article
Abstract: Dr. Tychele Turner is an assistant professor of genetics at the Washington University in St. Louis. This issue of Cell Genomics presents research from her lab in "Proteome-wide assessment of differential missense variant clustering in neurodevelopmental disorders and cancer" by Ng et al. This paper used their newly developed program, 3D-CLUMP, which can perform proteome-wide significant case-control analysis and clustering of protein-coding variants related to disease. Using 3D-CLUMP, they examine how patients with mostly cancer or neurodevelopmental disorders (NDDs) are observed to have the same gene, even if the specific mutations causing them are not shared.
Source: Cell Genomics
Author: Tychele N. Turner
Language: English
Topic: Genomics and Rare Diseases
Subfield: Genetics
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $8,900
OpenAlex ID: W4409283358