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Right Ventricular Function and Afterload Following Novel Transcatheter Tricuspid Valve Replacement

Year: 2025

Type: article

Abstract: Right ventricular (RV) function is an important determinant of prognosis in pulmonary hypertension and valvular heart disease. The accurate assessment of RV function is however limited by the presence of concomitant tricuspid regurgitation (TR). Implantation of a novel transcatheter tricuspid valve device in this case highlights the importance of recognizing these limitations, and the need to define alternative ways to measure RV systolic function, contextualized to pulmonary pressure in patients with severe TR. It also demonstrates the clinical potential of perforation of the pop-off zone in this prosthesis, to create mild residual TR, thereby reducing the increase in RV afterload of this intervention, and its impact on RV systolic function.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2025.103312

Authors: Hannah Kempton, Mayooran Namasivayam, Thomas Meredith, Martin Shaw, Paul Jansz, David W.M. Muller

Institutions: UNSW Sydney, St Vincent's Hospital Sydney, Victor Chang Cardiac Research Institute

Language: English

Topic: Cardiac Valve Diseases and Treatments

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $850