Work

Pregnancy After Fertility Sparing Surgery in Advanced Ovarian Low-grade Papillary Serous Carcinoma: A Case Report

Year: 2025

Type: article

Abstract: Ovarian Low-grade serous carcinoma (LGSC), a type of epithelial ovarian tumor, is often diagnosed in the advanced stage. Treatment involves surgery and chemotherapy. In advanced stages (3 and 4), removing all tumoral implants with both the uterus and ovaries (debunking surgery) is the first surgical goal. We presented a case of a 38-year-old woman who became pregnant three years after being diagnosed with LGSOC at stage 3c. We resected all tumoral implants, and decision was made to preserve the uterus for her since the patient wanted to be pregnant. The patient underwent surgery, then followed by a standard chemotherapy regime. During the three years of follow-up, there were no signs of tumor return; she decided to get pregnant by egg donation through an in vitro fertilization (IVF) procedure. A cesarean section was done, and the twin infants were born in good condition and with good APGAR scores.

Source: Journal of Obstetrics Gynecology and Cancer Research

DOI: 10.30699/jogcr.10.5.424

Authors: Malihe Hasanzadeh, Hamid Mollazadeh, Mohammad Montazami Sadeghi, Elham Sharafkhani

Institutions: Mashhad University of Medical Sciences, North Khorasan University of Medical Sciences

Language: English

Topic: Ovarian cancer diagnosis and treatment

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4409286797